abstract：:Cytomegalovirus (CMV) has been implicated in vascular pathologies and may warrant inclusion in cardiovascular predictive algorithms. We addressed this in healthy older adults and renal transplant recipients (RTR) as they retain a high burden of CMV. RTR (n  =  45) stable more than 2 years after transplantation and 58 ...

journal_title：Journal of medical virology

authors： Affandi JS,Lee S,Chih H,Brook E,Waters S,Howson P,Reid CM,Irish A,Price P

更新日期：2020-02-04 00:00:00

abstract：:Chikungunya fever is a viral disease transmitted to humans by the bite of infected mosquitoes. The disease is characterized by fever, headache, rash, severe joint, and muscle pain. To evaluate the disease burden in the population and the effectiveness of public health measures, periodic seroprevalence surveys are esse...

journal_title：Journal of medical virology

authors： Shilpa C,Kavitha K,Sudheesh N,Sabeena S,Prasad V,Hindol M,Arunkumar G

更新日期：2020-01-01 00:00:00

abstract：:Cytomegalovirus (CMV) infection remains a major complication after allogeneic hematopoietic cell transplantation (allo-HCT). We conducted a retrospective study to determine the clinical and economic burden of pre-emptive therapy (PET) for CMV infection in 100 consecutive hospitalized adult CMV positive serostatus allo...

journal_title：Journal of medical virology

authors： El Haddad L,Ghantoji SS,Park AK,Batista MV,Schelfhout J,Hachem J,Lobo Y,Jiang Y,Rondon G,Champlin R,Chemaly RF

更新日期：2020-01-01 00:00:00

abstract：:Human papillomavirus (HPV) detection is used for screening of cervical cancer and genotype-specific persistence has shown to be mandatory for dysplasia development. Aim of this study was to evaluate the clinical performance of HPV DNA Array for cervical intraepithelial neoplasia 2+ (CIN2+)  lesion detection. HPV DNA A...

journal_title：Journal of medical virology

authors： Pesic A,Krings A,Hempel M,Preyer R,Kaufmann AM

更新日期：2020-01-01 00:00:00

abstract：:Recently, human platelet antigens (HPAs) polymorphisms are found to play a role in susceptibility to hepatitis C virus (HCV) infection and fibrosis progression. The aim of the current study was to evaluate the possible association between the HPAs polymorphisms with liver fibrosis progression in HCV patients. HPAs pol...

journal_title：Journal of medical virology

authors： Ghasemi A,Zadsar M,Shaiegan M,Samiei S,Namvar A,Rasouli M,Moosanejad M

更新日期：2020-01-01 00:00:00

abstract：AIMS:Little data have been published so far on the epidemiological aspects of hepatitis D virus (HDV) infection in immigrant populations and even poorer is the information on the virological, phylogenetic, and clinical aspects of this infection in these populations. This review article, aimed primarily at physicians ca...

journal_title：Journal of medical virology

authors： Coppola N,Alessio L,Onorato L,Sagnelli C,Sagnelli E,Pisaturo M

更新日期：2019-12-01 00:00:00

abstract：:The expression levels of many genes change after treatment of human immunodeficiency virus (HIV)-infected subjects by antiretroviral drugs. High-throughput analysis of tremendous datasets led to the discovery of genes that are implicated in the treatment pathways. In this study, we performed a gene-enrichment analysis...

journal_title：Journal of medical virology

authors： Mozhgani SH,Zarei Ghobadi M,Behnam Rad M,Farzanehpour M,Behzadian F

更新日期：2019-12-01 00:00:00

abstract：:Coinfections with multiple types of human papillomavirus (HPV) occur in cervical adenocarcinoma (ADC). However, it remains unclear the clustering patterns of multiple types in HPV coinfections and relevant factors in ADC. A total of 718 paraffin-embedded ADC specimens were collected in China and tested for HPV genotyp...

journal_title：Journal of medical virology

authors： Dong L,Li T,Li L,Wang MZ,Wu Z,Cui J,Liu B,Zhang X,Qiao Y,Chen W

更新日期：2019-11-01 00:00:00

abstract：:BKPyV replication is a risk factor for the development of polyomavirus-associated nephropathy in kidney transplant recipients. Here, the case of a 42 years old Caucasian patient is described who developed a kidney allograft failure because of uncontrolled BKPyV replication 7 months after transplant despite a strong re...

journal_title：Journal of medical virology

authors： Anselmo A,Prezioso C,Saccà FA,Di Lella FM,Palmieri G,Tisone G,Pietropaolo V,Ciotti M

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND AND AIM:The hepatitis B virus (HBV) prevalence study performed in 2003 in Belgium is believed to be underestimating HBV prevalence due to underrepresentation of the non-Belgian population. Therefore, we assessed the prevalence and risk factors of HBV infection in a multi-ethnic region situated in Middle-Limb...

journal_title：Journal of medical virology

authors： Koc ÖM,Kremer C,Bielen R,Buscchots D,Hens N,Nevens F,Robaeys G

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:The data on the seasonality of respiratory viruses helps to ensure the optimal vaccination period and to monitor the possible outbreaks of variant type. OBJECTIVES:This study was designed to describe the molecular epidemiology and seasonality of acute respiratory infection (ARI)-related respiratory viruses ...

journal_title：Journal of medical virology

authors： Jeon JH,Han M,Chang HE,Park SS,Lee JW,Ahn YJ,Hong DJ

更新日期：2019-08-01 00:00:00

abstract：:No controlled trial in patients with chronic hepatitis B virus (HBV) infection on long-term entecavir (ETV) treatment, comparing switching to tenofovir disoproxil fumarate (TDF) with continuing the therapy, has been reported. Twenty-seven nucleos(t)ide-naïve patients with chronic HBV who underwent ETV therapy for ≥5 y...

journal_title：Journal of medical virology

authors： Iida-Ueno A,Enomoto M,Kozuka R,Tamori A,Kawada N

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND AND AIM:Genotype 3b hepatitis C virus (HCV) infection represents approximately 50% of patients with genotype 3 in China. We compared the efficacy of sofosbuvir (SOF) plus ribavirin (RBV) in Chinese patients with genotype 3a and 3b HCV. METHODS:The analyzed data are from a phase 3, open-label study of SOF pl...

journal_title：Journal of medical virology

authors： Huang R,Rao H,Xie Q,Gao Z,Li W,Jiang D,Mo H,Massetto B,Stamm LM,Brainard DM,Wei L

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Human metapneumovirus (hMPV) is a recently detected virus, which can cause mild to severe respiratory tract infections. Through this study, we aimed to detail the outcomes of hMPV infections. MATERIALS/METHODS:Between January 2012 and November 2017, patients who had hMPV detected in nasopharyngeal or bronch...

journal_title：Journal of medical virology

authors： Keske Ş,Gümüş T,Köymen T,Sandıkçı S,Tabak L,Ergönül Ö

更新日期：2019-06-01 00:00:00

abstract：:It has been reported that low-plasma cytomegalovirus (CMV) DNA loads are associated with an increased risk of overall mortality in allogeneic hematopoietic stem cell transplantation (allo-HSCT). Utilizing a conservative strategy for initiation of preemptive antiviral therapy (>1500 IU/mL), we characterized the virolog...

journal_title：Journal of medical virology

authors： Talaya A,Giménez E,Piñana JL,Albert E,Hernández-Boluda JC,Pérez A,Torres I,Solano C,Navarro D

更新日期：2019-06-01 00:00:00

abstract：AIMS:To investigate the association between two RIG-I-like receptor gene polymorphisms and hepatitis C virus (HCV) infection in Chinese Han population. METHODS:The current study genotyped two selected SNPs (IFIH1 rs3747517 and DDX58 rs9695310) using TaqMan allelic discrimination assay to assess their association with ...

journal_title：Journal of medical virology

authors： Zhu XB,Zhuo LY,Yue M,Liu M,Zang F,Fan HZ,Wu JJ,Xia XS,Zhang AM,Yu RB,Huang P

更新日期：2019-06-01 00:00:00

abstract：:Norovirus (NoV) is a major cause of nonbacterial acute gastroenteritis (AGE) outbreaks worldwide, with infections reported in semiclosed environments, particularly in hospitals and nursing homes. Astrovirus (HAstV) is prevalent worldwide, especially in developing countries. We aimed to determine the prevalence, spatia...

journal_title：Journal of medical virology

authors： Bitencurt ELR,Siqueira JAM,Medeiros TB,Bandeira RDS,de Souza Oliveira D,de Paula Souza E Guimarães RJ,da Silva Soares L,Macarenhas JDP,Teixeira DM,Silva RSU,Loureiro ECB,de Moraes Silva MC,da Silva LD,Gabbay YB

更新日期：2019-06-01 00:00:00

abstract：:Varicella-zoster virus (VZV)-specific cell-mediated immunity (CMI) is critical for preventing and controlling the onset of herpes zoster (HZ). To assess VZV CMI, an interferon-γ (IFN-γ) enzyme-linked immunosorbent assay (ELISA) was validated by examining the influence of VZV-specific antigen content, incubation time, ...

journal_title：Journal of medical virology

authors： Yang P,Chen Z,Zhang J,Li W,Zhu C,Qiu P,Quan Y,Cui X,Yuan L,Jiang C

更新日期：2019-05-01 00:00:00

abstract：:Latency associated peptide (LAP) is a protein expressed on the membrane of some regulatory T cells (Treg). LAP+ Treg have a greater immunomodulatory effect than that of their negative counterparts. In this study, we presented the data on the proportion of LAP+ Treg out of CD4+ cells in mice with viral myocarditis, whi...

journal_title：Journal of medical virology

authors： Wang X,Ge J,Chen R

更新日期：2019-05-01 00:00:00

abstract：:Interleukin 6 (IL-6) is a pleiotropic cytokine with pivotal functions in the regulation of the biological responses of several target cells, including hepatocytes. Previous studies have shown that serum IL-6 levels are increased in hepatitis B patients. However, the role of IL-6 in modulating the anti-hepatitis B viru...

journal_title：Journal of medical virology

authors： Yang K,Guan S,Zhang H,Chen Z

更新日期：2019-05-01 00:00:00

abstract：:Seoul virus (SEOV) is the etiologic agent of hemorrhagic fever with renal syndrome. It is carried by brown rats (Rattus norvegicus), a commensal rodent that closely cohabitates with humans in urban environments. SEOV has a worldwide distribution, and in Europe, it has been found in rats in UK, France, Sweden, and Belg...

journal_title：Journal of medical virology

authors： Ling J,Verner-Carlsson J,Eriksson P,Plyusnina A,Löhmus M,Järhult JD,van de Goot F,Plyusnin A,Lundkvist Å,Sironen T

更新日期：2019-05-01 00:00:00

abstract：:Liver fibrosis is accelerated in human immunodeficiency virus/hepatitis C virus (HIV/HCV) coinfected compared with HCV monoinfected patients, due to multiple cofactors. Recently, HLA-B18 haplotype has been associated with short-term liver disease progression in this population. Our aim was to assess the influence of H...

journal_title：Journal of medical virology

authors： Bavaro DF,Saracino A,Fiordelisi D,Bruno G,Ladisa N,Monno L,Angarano G

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Acute respiratory infection (ARI) is a leading cause of morbidity and mortality in children in low and middle-income countries. Human metapneumovirus (hMPV) is one of the most common viral etiological agents for ARIs in children. OBJECTIVES:In this study, we explored the genotypic diversity and the epidemio...

journal_title：Journal of medical virology

authors： Rahman MZ,Sumiya M,Sahabuddin M,Pell LG,Gubbay JB,Rahman R,Momtaz F,Azmuda N,Shanta SS,Jahan I,Rahman M,Mahmud AA,Roth DE,Morris SK

更新日期：2019-04-01 00:00:00

abstract：:Severe hand, foot, and mouth disease (HFMD) is sometimes associated with critical complications that can cause substantial child mortality. Activity of the vitamin D receptor (VDR) may influence the outcomes of enterovirus 71 (EV71) infection. This case-control study aimed to assess the association of single-nucleotid...

journal_title：Journal of medical virology

authors： Li YP,Deng HL,Xu LH,Wang MQ,Li M,Zhang X,Dang SS

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Patients with thalassemia may also have cardiac abnormalities due to congenital problems, anemia, and increased burden of iron in their myocardium. This study was designed to evaluate the effects of direct acting antiviral (DAA) therapy on the cardiac function of hepatitis C virus (HCV)-infected patients wit...

journal_title：Journal of medical virology

authors： Khosravi A,Karimi-Sari H,Abedi-Andani M,Behnava B,Namvar A,Anvar A,Alavian SM

更新日期：2019-03-01 00:00:00

abstract：:To our knowledge, there are no published data on hepatitis C virus (HCV) genotypes in Angola. This study aimed at assessing the distribution of HCV genotypes in seropositive hemodialysis patients in Luanda. Among 51 HCV-positive subjects included, viremia was detected in 27 (53%). HCV genotyping was performed by bidir...

journal_title：Journal of medical virology

authors： da Costa Marques Borges LF,Zalis MG,Santoro-Lopes G,Varella RB

更新日期：2019-03-01 00:00:00

abstract：:The detection of hepatitis B virus (HBV) DNA plays a critical role in determining the level of viral replication in HBV-infected patients. However, how to select appropriate HBV DNA detection method, low-sensitivity (ls) and hypersensitivity (hs) remains unclear. In this study, hepatitis B surface antigen (HBsAg), hep...

journal_title：Journal of medical virology

authors： Liu C,Wu W,Shang S,Huang E,Xun Z,Lin J,Chen T,Yang B,Chen J,Ou Q

更新日期：2019-02-01 00:00:00

abstract：:We have tested a multiplex polymerase chain reaction (PCR) human papillomavirus (HPV) genotyping assay to fill the need for rapid and low-cost HPV detection in Sub-Saharan Africa. This method allows high throughput genotyping and simultaneous detection of 14 high-risk and two low-risk HPV types, by PCR amplification o...

journal_title：Journal of medical virology

authors： Samwel K,Kahesa C,Mwaiselage J,Gonzalez D,West JT,Wood C,Palefsky J,Angeletti PC

更新日期：2019-02-01 00:00:00

abstract：:In real-world settings, not much information is probably available on the treatment efficacy of the combination of glecaprevir and pibrentasvir (G/P) as a salvage therapy in failures of prior direct-acting antiviral (DAA) regimens. Especially, the evolution of NS5A resistance-associated variants (RAVs) and treatment e...

journal_title：Journal of medical virology

authors： Akuta N,Sezaki H,Suzuki F,Fujiyama S,Kawamura Y,Hosaka T,Kobayashi M,Kobayashi M,Saitoh S,Suzuki Y,Arase Y,Ikeda K,Kumada H

更新日期：2019-01-01 00:00:00

abstract：:To determine the seroprevalence of antibodies against dengue virus (DENV) and West Nile virus (WNV) in the human population of the Bolivian Chaco, we tested 256 inhabitants of two rural communities. The seroprevalence, confirmed by plaque reduction neutralization test, was 7.8% and 2.7% for DENV and WNV, respectively....

journal_title：Journal of medical virology

authors： Bartoloni A,Remoli ME,Farchi F,Zammarchi L,Fortuna C,Benedetti E,Ciufolini MG,Macchioni F,Rojas P,Lara Y,Padilla C,Roselli M,Mantengoli E,Mantella A,Tolari F,Paredes GA,Monasterio J,Valdarchi C,Venturi G,Rezza G

更新日期：2019-01-01 00:00:00

abstract：:Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne disease caused by the Crimean-Congo hemorrhagic fever virus. Long non-coding RNAs (lncRNAs) are generally classified as transcripts longer than 200 nucleotides (nt). The various lncRNAs expressed in infected cells are responsible for regulating the expression of v...

journal_title：Journal of medical virology

authors： Bayyurt B,Arslan S,Engin A,Bakir M

更新日期：2018-12-01 00:00:00

abstract：:Asymptomatic carriers have a major influence on the spreading of norovirus infections. The objective of this study was to examine the characteristics of patients and asymptomatic carriers affected by norovirus-related community gastroenteritis outbreaks. No significant difference between the two groups was observed in...

journal_title：Journal of medical virology

authors： Mori K,Konishi N,Suzuki Y,Harada S,Maeda M,Akase S,Obata H,Monma C,Nagano M,Kimoto K,Oda M,Somura Y,Hirai A,Shinkai T,Noda M,Sadamasu K

更新日期：2018-12-01 00:00:00

abstract：:Human sapoviruses (SaVs) are a common cause of the acute gastroenteritis epidemic worldwide, and SaV outbreaks and infections have become more frequent in recent years. Since the end of December, 2015 to December, 2016, 2 gastroenteritis outbreaks occurred in 2 kindergarten classes (outbreaks A and B) in the Baoan dis...

journal_title：Journal of medical virology

authors： Wang Md J,Li PhD Y,Kong Md X,Li PhD H,Zhang Ba Q,Jin PhD M,Wang PhD Y,Duan PhD Z

更新日期：2018-11-01 00:00:00

abstract：:Immune correlates of protection against human cytomegalovirus (HCMV) infection are still debated. This study aimed to investigate which arm of the immune response plays a major role in protection against HCMV infection in kidney transplant recipients (n = 40) and heart transplant recipients (n = 12). Overall, patients...

journal_title：Journal of medical virology

authors： Lilleri D,Zelini P,Fornara C,Zavaglio F,Rampino T,Perez L,Gabanti E,Gerna G

更新日期：2018-10-01 00:00:00

abstract：:Primary HIV-1 infections (PHI) with non-B subtypes are increasing in developed countries while transmission of HIV-1 harboring antiretroviral resistance-associated mutations (RAMs) remains a concern. This study assessed non-B HIV-1 subtypes and RAMs prevalence among patients with PHI in university hospitals of Marseil...

journal_title：Journal of medical virology

authors： Tamalet C,Tissot-Dupont H,Motte A,Tourrès C,Dhiver C,Ravaux I,Poizot-Martin I,Dieng T,Tomei C,Bregigeon S,Zaegel-Faucher O,Laroche H,Aherfi S,Mokhtari S,Chaudet H,Ménard A,Brouqui P,Stein A,Colson P

更新日期：2018-10-01 00:00:00

abstract：:Prophylactic antiviral therapy is recommended for hepatitis B virus (HBV)-infected patients with malignancies who are undergoing systemic chemotherapy. In the current study, we aimed to develop a risk scoring system to guide the selection of prophylactic antiviral agents. In this retrospective analysis, we included co...

journal_title：Journal of medical virology

authors： Kim HY,Yoo JJ,Oh S,Yu SJ,Kim YJ,Yoon JH,Kim W,Jung YJ,Kim BH,Kim CM,Park JW,Lee JH

更新日期：2018-10-01 00:00:00

abstract：:Rotavirus A (RVA) is the leading cause of acute viral gastroenteritis in children under 5 years of age worldwide. G9P[8] is a common RVA genotype that has been persistently prevalent in Jiangsu, China. To determine the genetic diversity of G9P[8] RVAs, 7 representative G9P[8] strains collected from Suzhou Children's H...

journal_title：Journal of medical virology

authors： Xu C,Fu J,Ai J,Zhang J,Liu C,Huo X,Bao C,Zhu Y

更新日期：2018-09-01 00:00:00

abstract：:Despite a significant decrease in acute hepatitis A in the last 2 decades in Italy, outbreaks were observed occurring mostly in southern Italy. In this study, Bayesian phylogenetic analysis was used to analyze the origin of these epidemics. With this aim, 5 different data sets of hepatitis A virus sequences were built...

journal_title：Journal of medical virology

authors： Cella E,Riva E,Angeletti S,Fogolari M,Blasi A,Scolamacchia V,Spoto S,Bazzardi R,Lai A,Sagnelli C,Sagnelli E,Ciccozzi M

更新日期：2018-09-01 00:00:00

abstract：:Human parechoviruses (HPeVs) are prevalent in young children; however, their effects are incompletely understood. We investigated the prevalence, genotype distribution, and phylogeny of HPeVs in individuals with diarrhea (n = 430) and healthy controls (n = 93) by the analysis of stool specimens collected from July 201...

journal_title：Journal of medical virology

authors： Chen X,Shi T,Huang J,Xiao G,Huang J,Xiong Y,Li X,Chen H,Zheng X,Yu S,Chen Q

更新日期：2018-09-01 00:00:00

abstract：:Hepatitis E virus (HEV) is a feco-orally transmitted pathogen and one of the most common cause of acute hepatitis worldwide. Recent studies in developed countries suggested that a direct human-to-human contact such as for sexually transmitted diseases may play a significant role in the HEV spread. The aim of this stud...

journal_title：Journal of medical virology

authors： Greco L,Uceda Renteria SC,Guarneri D,Orlandi A,Zoccoli A,Benardon S,Cusini M,Lunghi G

更新日期：2018-08-01 00:00:00